MetaMouse®
Orthotopic mouse models of all human cancer types. The most
clinically-realistic mouse models (click
here).
Imageable metastatic orthotopic cancer models of all types GFP- and
RFP- expressing tumors
http://www.youtube.com/watch?v=Jq8ybhCPG2s
OncoBrite®
Fluorescent protein-expressing cancer cell lines and mice. The most
powerful small-animal imaging technology (click
here).
Dynamic Fluorescence of Cancer in vivo
- part 1:
www.youtube.com/watch?v=MVBblPOmQUc
Dynamic Fluorescence of Cancer in vivo
- part 2:
www.youtube.com/watch?v=4qLpxfkFlCQ
Methioninase (rMETase)
Cancer-targeting therapeutic enzyme. Targets the methioninase
dependence of cancers. The only known general metabolic defect in
cancer.
HDRA
Histoculture drug response assay. 3-D sponge-gel culture of patient
tumors for identification of effective drugs for each patient. High
correlation with clinical outcome. For precision and individualized
cancer therapy (click
here).
Histoculture drug response assay for drug discovery and
individual patient treatment
https://www.youtube.com/watch?v=1TBNJoPBl3o
A/C Diagnostics
Diagnostic kits for homocysteine (Hcy) – World’s most sensitive Hcy
test (5 µl plasma or serum); world’s only non-radioactive vitamin B6
enzymatic assay; enzymatic cysteine assay for obesity propensity (click
here).
Homocysteine
enzymatic assay
The Homocysteine Factor
Vitamin B6
enzymatic assay
http://www.youtube.com/watch?v=8GrSnQxUA88
DermaTek®
3-D sponge-gel culture of human or mouse skin to evaluate
hair-growth therapeutics including hair-follicle targeted delivery (click
here).
AngioMouse®
Imageable mouse models of angiogenesis nascent blood vessels express
GFP. All blood vessels express RFP. Angiogenesis stimulates or
inhibits assays (click
here).
Stem Cells
Hair follicle-associated pluripotent stem cells (HAPS cells) can
differentiate to nerve, glial, and many other cell types, many
advantages over iPS and ES cells for regenerative medicine (click
here).
AntiCancer Inc. discovers new source
of stem cells in hair follicle that repairs nerve and spinal cord
injury -
http://www.youtube.com/watch?v=azwvp7pkEEo
Bacterial Therapy of Cancer
Salmonella typhimurium A1-R engineered to target all cancer types
and eradicate them. Most promising upcoming cancer therapy
(click
here).
Tumor-Killing Bacteria -
http://www.youtube.com/watch?v=y5TNRW1_VZI
Circulating Tumor Cells (CTCs)
Cancer cells, circulating in the blood, labeled with GFP can be used
for diagnosis to prognosis and therapeutic testing
(click
here).
Cancer Stem Cells
Cancer stem and non-stem cells can be color-coded with fluorescent
proteins and targeted for novel therapy in mouse models
(click
here).
CFP Nude Mouse
(click
here)
GFP Nude Mouse (click
here)
Nestin-GFP Mouse
RFP Nude Mouse
Fluorescent protein-expressing mouse models, immunocompetent and
nude to color code tumor and host for visual therapeutic targets
(click
here).
Stroma Mouse
Color-coded mouse models to visualize all cell types in the tumor
microenvironment as visual targets for stroma therapy
(click
here).
Fluorescence-guided UV-Photo-Dynamic Therapy (PDT)
PDT of fluorescently-labeled cancer cells for enhanced efficacy.
Novel approach to eradication of residual cancer after surgery or
chemotherapy (click
here).
Fluorescence-guided Surgery and Laparoscopy
In vivo labeling of tumors with a cancer-specific GFP-adenovirus or
fluorescent antibodies to enhance tumor and metastasis visualization
by the surgeon for curative cancer resection (click
here).
FUCCI (Fluorescence Ubiquitination-based Cell Cycle Indicator)
Color codes each cell-cycle phase. Useful for developing cell
cycle-decoy and trap therapy for a new paradigm of cancer therapy
(click here).
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