1. Yang,
M., Baranov, E., Li, X-M., Wang, J-W., Jiang, P., Li, L., Moossa, A.R., Penman,
S., Hoffman, R.M. Whole‑body and intravital optical imaging of angiogenesis in
orthotopically implanted tumors. Proc. Natl. Acad. Sci. USA 98, 2616-2621, 2001.
2. Yang,
M., Baranov, E., Wang, J-W., Jiang, P., Wang, X., Sun, F-X., Bouvet, M., Moossa,
A.R., Penman, S., and Hoffman, R.M. Direct external imaging of nascent cancer,
tumor progression, angiogenesis, and metastasis on internal organs in the
fluorescent orthotopic model. Proc. Natl. Acad. Sci. USA 99, 3824-3829, 2002.
3. Yang,
M., Li, L., Jiang, P., Moossa, A.R., Penman, S., and Hoffman, R.M. Dual-color
fluorescence imaging distinguishes tumor cells from induced host angiogenic
vessels and stromal cells. Proc. Natl. Acad. Sci. USA 100, 14259-14262, 2003.
4. Amoh,
Y., Li, L., Yang, M., Moossa, A.R., Katsuoka, K., Penman, S., and Hoffman, R.M.
Nascent blood vessels in the skin arise from nestin-expressing hair follicle
cells. Proc. Natl. Acad. Sci. USA 101, 13291-13295, 2004.
5. Yang,
M., Reynoso, J., Jiang, P., Li, L., Moossa, A.R., and Hoffman, R.M. Transgenic
nude mouse with ubiquitous green fluorescent protein expression as a host for
human tumors. Cancer Research 64, 8651-8656, 2004.
6. Hoffman,
R.M. The multiple uses of fluorescent proteins to visualize cancer in vivo.
Nature Reviews Cancer 5, 796-806, 2005.
7. Amoh,
Y., Li, L., Yang, M., Jiang, P., Moossa, A.R., Katsuoka, K., and Hoffman, R.M.
Hair follicle-derived blood vessels vascularize tumors in skin and are inhibited
by doxorubicin. Cancer
Res. 65, 2337-2343.
2005.
8. Amoh,
Y., Yang, M., Li, L., Reynoso, J., Bouvet, M., Moossa, A.R., Katsuoka, K., and
Hoffman, R.M. Nestin-linked green fluorescent protein transgenic nude mouse for
imaging human tumor angiogenesis. Cancer Res. 65, 5352-5357, 2005.
9. Hoffman,
R.M., and Yang, M. Color-coded fluorescence imaging of tumor-host
interactions. Nature Protocols 1, 928-935, 2006.
10. Amoh,
Y., Li, L., Tsuji, K., Moossa, A.R., Katsuoka, K., Hoffman, R.M., Bouvet, M.
Dual-color imaging of nascent blood vessels vascularizing pancreatic cancer in
an orthotopic model demonstrates antiangiogenesis efficacy of gemcitabine.
J. Surgical Research 132, 164-169, 2006.
11. Amoh,
Y., Nagakura, C., Maitra, A., Moossa, A.R., Katsuoka, K., Hoffman, R.M., and
Bouvet, M. Dual-color imaging of nascent angiogenesis and its inhibition in
liver metastases of pancreatic cancer. Anticancer Research
26,
3237-3242, 2006.
12.
Amoh, Y., Bouvet, M., Li, L., Tsuji, K., Moossa, A.R., Katsuoka,
K., and Hoffman, R.M. Visualization of nascent tumor angiogenesis in lung and
liver metastasis by differential dual-color fluorescence imaging in nestin-linked-GFP
mice. Clin. Exp. Metastasis
23(7-8),
315-322, 2006.
13.
Hoffman, R.M. AngioMouse: imageable models of angiogenesis. In:
Angiogenesis Assays: A critical appraisal of current techniques, pp. 293-310.
Staton, C.A., Lewis, C., and Bicknell, R., eds. Wiley and Sons, 2006.
14.
Amoh, Y., Li, L., Katsuoka, K.,
Bouvet, M., and Hoffman, R.M. GFP-expressing vascularization of Gelfoam as a
rapid in vivo assay of angiogenesis stimulators and inhibitors.
BioTechniques 42,
294-298, 2007.
15.
Ji, Y.,
Hayashi, K., Amoh, Y., Tsuji, K., Yamauchi, K., Yamamoto, N., Tsuchiya, H.,
Tomita, K., Bouvet, M., and Hoffman, R.M. The camptothecin derivative CPT-11
inhibits angiogenesis in a dual-color imageable orthotopic metastatic nude mouse
model of human colon cancer. Anticancer Res.
27,
713-718, 2007.
16.
Hayashi,
K., Yamauchi, K., Yamamoto, N., Tsuchiya, H., Tomita, K., Amoh, Y., Hoffman, R.M.,
and Bouvet, M. Dual-color imaging of angiogenesis and its inhibition in bone and
soft tissue sarcoma. J. Surg. Res. 140, 165-170, 2007.
17.
Hayashi,
K., Jiang, P., Yamauchi, K., Yamamoto, N., Tsuchiya, H., Tomita, K., Moossa, A.R.,
Bouvet, M., and Hoffman, R.M. Real-time imaging of tumor-cell shedding and
trafficking in lymphatic channels. Cancer Res. 67, 8223-8228, 2007.
18.
Amoh, Y.,
Katsuoka, K., and Hoffman, R.M. Color-coded fluorescent protein imaging of
angiogenesis: the AngioMouse models. Curr. Pharm. Des. 14, 3810-3819, 2008.
19.
Hayashi,
K., Yamauchi, K., Yamamoto, N., Tsuchiya, H., Tomita, K., Bouvet, M., Wessels,
J., and Hoffman, R.M. A color-coded orthotopic nude-mouse treatment model of
brain-metastatic paralyzing spinal cord cancer that induce angiogenesis and
neurogenesis. Cell Proliferation 42, 75-82, 2009.
20.
Yang, M.,
Reynoso, J., Bouvet, M., and Hoffman, R.M. A transgenic red fluorescent
protein-expressing nude mouse for color-coded imaging of the tumor
microenvironment. J. Cell. Biochem. 106, 279-284, 2009.
21.
Daenen, L.G., Shaked, Y., Man, S., Xu, P., Voest, E.E., Hoffman, R.M., and
Kerbel, R.S. Low-dose metronomic cyclophosphamide combined with vascular
disrupting therapy induces potent antitumor activity in preclinical human tumor
xenograft models. Molecular Cancer Therapeutics 8,
2872-2881, 2009.
22.
Folkins, C., Shaked, Y., Man, S., Tang, T., Lee, C.R., Zhu, Z., Hoffman, R.M.,
and Kerbel, R.S. Glioma tumor stem-like cells promote tumor angiogenesis and
vasculogenesis via vascular endothelial growth factor and stromal-derived factor
1. Cancer Research 69,
7243-7251, 2009.
23.
Aki, R.,
Amoh, Y., Li, L., Katsuoka, K., Hoffman, R.M. Nestin-expressing interfollicular
blood vessel network contributes to skin transplant survival and wound healing. J
Cell Biochem. 110(1), 80-86,
2010.
24.
Liu,
F., Zhang, L., Hoffman, R.M., and Zhao, M. Vessel destruction by
tumor-targeting Salmonella
typhimurium A1-R is enhanced by
high tumor vascularity. Cell Cycle 9, 4518-4524,
2010. 
25.
Kioi, M., Vogel, H., Schultz, G., Hoffman, R.M., Harsh, G.R., and Brown, J.M.
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of
glioblastoma following irradiation in mice. Journal of Clinical Investigation 120,
694-705, 2010.
26.
Soda, Y., Marumoto, T., Friedmann-Morvinski,
D., Soda, M., Liu, F., Michiue, H., Pastorino, S., Yang,
M., Hoffman, R.M., Kesari, S., Verma, I.M. Transdifferentiation of glioblastoma
cells into vascular endothelial cells. Proc.
Natl. Acad. Sci. USA108, 4274-4280, 2011. Commentary: Hormigo, A., Ding, B-S., and Rafii,
S. A target for antiangiogenic therapy: Vascular endothelium derived from
glioblastoma. Proc. Natl. Acad. Sci. USA 108,
4271-4272, 2011.
27.
Zhang, Q., Bindokas, V.P., Shen, J., Fan, H., Hoffman, R.M., Xing, H.R.
Time-course imaging of therapeutic functional tumor vascular normalization by
anti-angiogenic agents. Mol.
Cancer Ther. 10, 1173-1184,
2011.

28.
Tome, Y., Zhang, Y., Momiyama, M., Maehara, H., Kanaya, F., Tomita, K.,
Tsuchiya, H., Bouvet, M., Hoffman, R.M.., and Zhao, M. Primer dosing of S.
typhimurium A1-R potentiates tumor-targeting and efficacy in immunocompetent
mice. Anticancer Res. 33, 97-102, 2013.
29.
Shi, Y., Tong, M., Wu, Y., Yang, Z., Hoffman, R.M., Zhang, Y., Tian, Y., Qi, M.,
Lin, Y., Liu, Y., Dai, L., Sun, Y., and Wang, Z. VEGF-C ShRNA inhibits
pancreatic cancer growth and lymphangiogenesis in an orthotopic fluorescent nude
mouse model. Anticancer Research 33, 409-417, 2013.
30.
Uehara, F., Tome, Y., Yano, S., Miwa, S., Mii, S., Hiroshima, Y., Bouvet, M.,
Maehara, H., Kanaya, F., and Hoffman, R.M. A color-coded imaging model of the
interaction of αv integrin-GFP expressed in osteosarcoma cells and RFP
expressing blood vessels in GelfoamŪ vascularized in vivo. Anticancer Res. 33,
1361-1366, 2013.
31.
Uehara, F., Tome, Y., Reynoso, J., Mii, S., Yano, S., Miwa, S., Bouvet, M.,
Maehara, H., Kanaya, F., Moossa, A.R., and Hoffman, R.M. Color-coded imaging of
spontaneous vessel anastomosis in vivo. Anticancer Research 33, 3041-3045.
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