Angiogenesis Models - AngioMouse

AngioMouse: Discover new effective drugs for angiogenesis in vivo (video )

LICENSING AND CONTRACT RESEARCH

Features                                                                                                                                    Examples

Visualization of tumor vessels using GFP tumor expression

  • Intravital imaging of tumor vessels

  • Whole-body imaging of tumor vessels

  • Quantitation of vessel density

  • Real-time angiogenesis studies

  • Angiogenesis drug discovery and evalation

  • Orthotopic models of all tumor types

 

 

 

Whole-body image of vessels in PC-3-GFP human prostate cancer in nude mouse.

 

Intravital image of ANIP-973-GFP human lung cancer in nude mouse.

 

Whole-body image of Lewis lung-GFP mouse carcinoma in nude mouse.

 

Whole-body images of time course of microvessel development in orthotopic model of MDA-MB-435-GFP human breast cancer.

EXTERNAL IMAGING OF MICROVESSELS OF GFP-EXPRESSING HUMAN PANCREATIC CANCER GROWING ON THE NUDE MOUSE PANCREAS VISUALIZED THROUGH A REVERSIBLE SKIN FLAP.

A - mouse imaged in light box, B - mouse imaged on dissecting microscope.