2 0 0 5   A A C R   P r e s e n t a t i o n s

 

96th Annual Meeting of the American Association for Cancer Research

April 16-20, 2005

Anaheim Convention Center

Anaheim, Orange County, California

 

 

Sunday, April 17, 2005

 

Abstract Number:                         205

Title:              Gene expression analysis of endothelial cell associated genes as potential progression markers of human melanoma

Authors:                          Go Nakajima, Yanguang Xi, Tray Hamil, Robert M Hoffman, Oystein Fodstad, Jingfang Ju

Poster Session ID:                          Tumor Biology 1

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         1069

Title:                          Characterization of the nestin-driven-GFP (ND-GFP) nude mouse and its uses in cancer research

Authors:                          Yasuyuki Amoh, Lingna Li, Meng Yang, Jose Reynoso, AR Moossa, Kensei Katsuoka, David Tarin, Robert M Hoffman

Poster Session ID:                         Tumor Biology 6

Session Start Time:                          1:00:00 PM

 

Abstract Number:                         1407

Title:                          PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates

Authors:              Zhijian Yang, Junhua Wang, Quan Lu, Jinbao Xu, Yoshinao Kobayashi, Tomoaki Takakura, Akio Takimoto, Takayuji Yoshioka, Changgen Lian, Chunmei Chen, Dongdong Zhang, Ying Zhang, Shukuan Li, Xinghua Sun, Yuying Tan, Shigeo Yagi, Eugene P Frenkel, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 9

Session Start Time:                         1:00:00 PM

 

Monday, April 18, 2005

 

Abstract Number:                         2049

Title:                          Identification of a multipotent nestin-positive, keratin-negative primitive stem cell in the hair follicle

Authors:                          Yasuyuki Amoh, Lingna Li, Kensei Katsuoka, Robert M Hoffman

Poster Session ID:                         Tumor Biology 15

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         2066

Title:                          Hair-follicle-derived blood vessels vascularize tumors in skin and are inhibited by doxorubicin

Authors:                          Yasuyuki Amoh, Lingna Li, Meng Yang, Ping Jiang, AR Moossa, Kensei Katsuoka, and Robert M Hoffman

Poster Session ID:                         Tumor Biology 15

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         2071

Title:                          Imaging the effect of chemotherapy on hair-follicle stem cells and associated blood vessels expressing GFP

Authors:                          Yasuyuki Amoh, Lingna Li, Kensei Katsuoka, and Robert M Hoffman

Poster Session ID:                         Tumor Biology 16

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         2370

Title:                          Sensitive assay of tumor S-adenosyl-methionine and S-adenosyl-homocysteine

Authors:              Shukuan Li, Zhijian Yang, Xinghua Sun, Xiao-Ming Li, Mingxu Xu, Huaiyu  Ma, Yuying Tan, Shigeo Yagi, Robert M Hoffman

Poster Session ID:                          Experimental and Molecular Therapeutics 21

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         2521

Title:                          Early trafficking of cancer cells imaged in live mice after portal vein injection

Authors:                          Kazuhiko Tsuji, Kensuki Yamauchi, Meng Yang, Ping Jiang, H Endo, Y Kanai, K Yamashita, AR Moossa, Robert M Hoffman

Minisymposium Session ID: Tumor Biology 17

Session Start Time:                          9:30:00 PM

 

Abstract Number:            3019

Title:                             Paradoxical response to chemotherapy of nude mice with orthotopic multidrug resistant H69AR human small cell lung carcinomas

Authors:                       Michael Heuser, Ping Jiang, Ming Zhao, Xiao-Ming Li, Robert M. Hoffman, Marijana Kopun, Heinrich D. Becker, Christof Granzow

Poster Session ID: Tumor Biology 23

Session Start Time: 1:00:00 PM

 

Abstract Number:                         3337

Title:                          Effects of drugs on cellular dynamics visualized in live cells labeled with GFP in the nucleus and RFP in the cytoplasm

Authors:                          Ping Jiang, Meng Yang, Mingxu Xu, AR Moossa, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 28

Session Start Time:                          1:00:00 PM

 

Tuesday, April 19, 2005

 

Abstract Number:                         3838

Title:                           Multi-color imaging of angiogenesis of orthotopic human tumors in the nestin-driven GFP nude mouse

Authors:                          Yasuyuki Amoh, Lingna Li, Meng Yang, Kensei Katsuoka, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         3840

Title:              Nuclear ejection, chromatin elongation and destruction:  A new mechanism of cancer cell death imaged during immune rejection

Authors:              Yasuyuki Amoh, Lingna Li, Kensuke Yamauchi, AR Moossa, Shichiro Miyazawa, Hidekazu Tamauchi, Yuko Hamada, Kensei Katsuoka, Robert M Hoffman

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         3844

Title:                          Color-coded imaging visualizes recombinant tumor cells formed in vivo

Authors:                          Anna B Glinskii, Olga Berezovska, Ping Jiang, Xiao-Ming Li, Meng Yang, Robert M Hoffman, Gennadi V Glinsky

Poster Session ID:                         Tumor Biology 27

Session Start Time:                           8:00:00 AM

 

Abstract Number:                         3835

Title:              Apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells

Authors:              Olga Berezovska, Aaron D Schimmer, Anna B. Glinskii, Clemencia Pinilla, Robert M Hoffman, John C Reed, Gennadi V Glinsky

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         3842

Title:                          Comparison of fluorescent protein imaging (FPI) and MRI of pancreatic tumors in nude mice

Authors:                          Matthew H Katz, Joseph Spernyak, Shinako Takimoto, AR Moossa, Richard Mazurchuk, Robert M Hoffman, Michael Bouvet

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         3839

Title:              New dual-color fluorescence models of RFP orthotopic human pancreatic cancer implanted in b-actin-driven and nestin-driven GFP nude mice.

Authors:                          Michael Bouvet, Yasuyuki Amoh, Shinako Takimoto, Matthew H Katz, Meng Yang, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         3843

Title:                          Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model

Authors:              Vladimir Bobek, Jiri Plachy, Daniela Pinterova, Katarina Kolostova, Michael Boubelik, Ping Jiang, Meng Yang, Robert M Hoffman

Poster Session ID:                         Tumor Biology 27

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5034

Title:                          Targeting of breast cancer with selected amino acid auxotrophic variants of GFP-expressing Salmonella typhmurium

Authors:                          Ming Zhao, Xiao-Ming Li, Meng Yang, Yin Yie, Xiuying Tan, Ping Jing, Zhijian Yang, Sanford Barsky, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 42

Session Start Time:                          1:00:00 PM

 

Abstract Number:                         5033

Title:                          Tumor-targeting bacterial therapy with amino-acid auxotrophs of GFP-expressing Salmonella typhimurium

Authors:              Ming Zhao, Meng Yang, Xiao-Ming Li, Ping Jiang, Eugene Baranov, Shukuan Li, Mingxu Xu, Sheldon Penman, and Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 42

Session Start Time:                          1:00:00 PM

 

Abstract Number:                         5112

Title:                          Anti-tumor efficacy of Spongistatin-2 compared to taxanes in human prostate cancer models

Authors:                          Ping Jiang, Clayton H Heathcock, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 45

Session Start Time:                          1:00:00 PM

 

Wednesday, April 20, 2005

 

Abstract Number:                         5672

Title:              Characterization of an imageable low-malignancy variants of prostate and colon cancer cells for chemoprevention studies

Authors:                          Ping Jiang, Meng Yang, Eugene Baranov, Yuying Tan, Lingna Li, Xiao-Ming Li, Levy Kopelovich, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5671

Title:                          Dual-color imaging of tumor cell and nuclear deformation in the living animal

Authors:              Kensuke Yamauchi, Norio Yamamoto, Meng Yang, Ping Jiang, Mingxu Xu, Hiroyuki Tsuchiya, Katsuro Tomita, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5669

Title:                          Imaging capillary migration of tumor cells in live animals

Authors:              Kensuke Yamauchi, Norio Yamamoto, Meng Yang, Ping Jiang, Mingxu Xu, Hiroyuki Tsuchiya, Katsuro Tomita, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5670

Title:                          An improved optically imageable metastatic model of human colon cancer orthotopically implanted on the cecum

Authors:                          Huaiyu Ma, Jinwei Wang, Xiao-Ming Li, Zhijian Yang, Meng Yang, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5660

Title:                          Bile-duct obstruction model imaged at the single-cell level

Authors:                          Kazuhiko Tsuji, Kensuki Yamauchi, Meng Yang, Ping Jiang, H Endo, Y Kanai, K Yamashita, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

                       


Abstract Number:                         5667

Title:                          GFP imaging of liver micrometastasis formation from cells trafficking in the portal vein

Authors:                          Jinwei Wang, Huaiyu Ma, Meng Yang, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                           8:00:00 AM

 

Abstract Number:                         5673

Title:                          Dual-color imaging of tumor cells and nuclear shape changes during extravasation in living mice

Authors:              Kensuke Yamauchi, Norio Yamamoto, Meng Yang, Ping Jiang, Mingxu Xu, Hiroyuki Tsuchiya, Katsuro Tomita, AR Moossa, Robert M Hoffman

Poster Session ID:                         Tumor Biology 41

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5917

Title:                          Imageable intratibial implantation model of GFP-expressing multiple myeloma cells

Authors:                          Meng Yang, Mingxu Xu, Zhijian Yang, Ping Jiang, Constantine Mitsiades, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 51

Session Start Time:                          8:00:00 AM

 

Abstract Number:                         5918

Title:                          Novel effective bisphosphonate identified by whole-body imaging of GFP prostate tumor growth in bone

Authors:                          Meng Yang, Jack Geller, Ping Jiang, Doug Burton, Leonard J Deftos, Eugene Baranov, AR Moossa, Robert M Hoffman

Poster Session ID:                         Experimental and Molecular Therapeutics 51

Session Start Time:                          8:00:00 AM